Article
Three VSX1 gene mutations, L159M, R166W, and H244R, are not associated with keratoconus.
Cornea - 1 Feb 2008
Tang Yongming G, Picornell Yoana, Su Xiaowen, Li Xiaohui, Yang Huiying, Rabinowitz Yaron S
Abstract excerpt
PURPOSE: Three mutations, L159M, R166W, and H244R, in the VSX1 gene have been recently reported to be associated with keratoconus by direct sequencing in familial panels. In an attempt to confirm this observation, we surveyed the same mutations of the VSX1 gene for a white sporadic keratoconus case-control panel and a larger familial panel to test its association with keratoconus. METHODS: A case-control panel,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.