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Physiological roles of semenogelin I and zinc in sperm motility and semen coagulation on ejaculation in humans

18 Jan 2008

Abstract excerpt

At ejaculation, human sperm are considered to be mechanically trapped and become immotile in the semen coagulum by binding to semenogelins (Sgs) from the seminal vesicle and zinc ions from the prostate. However, the physiological combined roles of the protein and heavy metal on sperm motility are unknown. Here, we have first demonstrated that Sg I alone, which does not form the semen coagulum without zinc, is an...

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PMID: 18203809
DOI: 10.1093/molehr/gan003

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