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Human Fusobacterium necrophorum strains have a leukotoxin gene and exhibit leukotoxic activity

17 Jan 2008

Abstract excerpt

Fusobacterium necrophorum, a Gram-negative anaerobe, causes a variety of necrotic infections in humans and animals. There are two subspecies: subsp. necrophorum and subsp. funduliforme. In cattle, subsp. necrophorum is more prevalent and production of leukotoxin is a major virulence factor. The leukotoxin operon (lktBAC) consists of three genes, lktB, lktA and lktC, of which lktA is the structural toxin gene. The...

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PMID: 18201990
DOI: 10.1099/jmm.0.47598-0

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