To what extent do scans of non-synonymous SNPs complement denser genome-wide association studies?

Abstract excerpt

Several studies involving genome-wide scans of non-synonymous SNPs (nsSNPs) have successfully identified loci contributing to common complex diseases. We were interested in the extent to which these small scans involving a few thousand non-synonymous markers might complement the results from denser genome-wide association studies. We assessed the degree to which three commercially available genome-wide marker...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Genome, Human
• Share to Polymorphism, Single Nucleotide