Article
The genotypic inhibitory quotient: a predictive factor of atazanavir response in HIV-1-infected treatment-experienced patients.
Journal of acquired immune deficiency syndromes (1999) - 1 Jun 2008
Solas Caroline, Colson Philippe, Ravaux Isabelle, Poizot-Martin Isabelle, Moreau Jacques, Lacarelle Bruno, Tamalet Catherine
Abstract excerpt
OBJECTIVE: To evaluate the predictive value of the genotypic inhibitory quotient (GIQ) on the atazanavir response in treatment-experienced HIV-1-infected patients. PATIENTS AND METHODS: Thirty-six patients receiving an atazanavir-containing regimen were enrolled in the study. Atazanavir plasma concentrations were measured at month (M) 1, and genotype was performed at baseline. Virologic response was defined as a...
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