Article
Transcript annotation prioritization and screening system (TrAPSS) for mutation screening.
Journal of bioinformatics and computational biology - 1 Dec 2007
O'Leary Brian M, Davis Steven G, Smith Michael F, Brown Bartley, Kemp Mathew B, Almabrazi Hakeem, Grundstad Jason A, Burns Thomas, Leontiev Vladimir, Andorf Jeaneen, Clark Abbot F, Sheffield Val C, Casavant Thomas L, Scheetz Todd E, Stone Edwin M, Braun Terry A
Abstract excerpt
When searching for disease-causing mutations with polymerase chain reaction (PCR)-based methods, candidate genes are usually screened in their entirety, exon by exon. Genomic resources (i.e. www.ncbi.nih.gov, www.ensembl.org, and genome.ucsc.edu) largely support this paradigm for mutation screeni...
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