Article
Portal CD4+ and CD8+ T lymphocyte correlate to intensity of interface hepatitis in chronic hepatitis C.
Revista do Instituto de Medicina Tropical de Sao Paulo - 1 Jan 2000
Viso Ana Teresa Rodriguez, de Castro Barbosa Thaís, Yamamoto Lídia, Pagliari Carla, Fernandes Elaine Raniero, Brasil Roosecelis Araújo, Andrade Heitor Franco de, Duarte Maria Irma Seixas, Barone Antônio Alci
Abstract excerpt
BACKGROUND: The pathogenesis of chronic hepatitis C is still a matter of debate. CD4+ and CD8+ T lymphocytes (TL) are typically observed within the portal and periportal spaces of affected livers, but their functional role in hepatitis C progression has not been fully elucidated. METHODS: CD4+ and CD8+ TL were quantified by immunohistochemistry in portal and periportal spaces of 39 liver biopsies from patients...
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