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Article

Analysis of hMLH1 missense mutations in East Asian patients with suspected hereditary nonpolyposis colorectal cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Dec 2007

Fan Yimei, Wang Wei, Zhu Ming, Zhou Jiji, Peng Jingyuan, Xu Lizhi, Hua Zichun, Gao Xiang, Wang Yaping

Abstract excerpt

PURPOSE: Germ line mutations in the DNA mismatch repair gene hMLH1 are a frequent cause of hereditary nonpolyposis colorectal cancer and about one-third of these are missense mutations. Several missense mutations in hMLH1 have frequently been detected in East Asian patients with suspected heredit...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Colorectal Neoplasms, Hereditary Nonpolyposis

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Identifiers

PMID: 18094436
DOI: 10.1158/1078-0432.CCR-07-1028

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18094436-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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