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Article

A neonatal encephalopathy with seizures in standard poodle dogs with a missense mutation in the canine ortholog of ATF2.

Neurogenetics - 1 Feb 2008

Chen Xuhua, Johnson Gary S, Schnabel Robert D, Taylor Jeremy F, Johnson Gayle C, Parker Heidi G, Patterson Edward E, Katz Martin L, Awano Tomoyuki, Khan Shahwanaz, O'Brien Dennis P

Abstract excerpt

Neonatal encephalopathy with seizures (NEWS) is a previously undescribed autosomal recessive disease of standard poodle puppies. Affected puppies are small and weak at birth. Many die in their first week of life. Those surviving past 1 week develop ataxia, a whole-body tremor, and, by 4 to 6 week...

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Source

Identifiers

PMID: 18074159
DOI: 10.1007/s10048-007-0112-2

Genes

ATF2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18074159-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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