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Article

Genetic interaction between the ero1-1 and leu2 mutations in Saccharomyces cerevisiae.

Bioscience, biotechnology, and biochemistry - 1 Dec 2007

López-Mirabal H Reynaldo, Winther Jakob R, Kielland-Brandt Morten C

Abstract excerpt

The conditional ero1-1 mutant, deficient in the ER-localized PDI oxidase Ero1p, is blocked in disulfide bond formation under restrictive conditions, such as high temperature, lack of oxygen, or high concentrations of membrane-permeant thiols. Previous studies of the physiological consequences of the ero1-1 mutation were carried out in a leu2 mutant. The ero1-1 leu2 strain does not grow in standard synthetic...

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PMID: 18071269
DOI: 10.1271/bbb.70323

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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