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Article

SMAD expression in the testis: An insight into BMP regulation of spermatogenesis

10 Dec 2007

Abstract excerpt

Bone morphogenetic proteins (BMPs), members of the transforming growth factor-beta superfamily, extensively influence events that establish male fertility, affecting germ cells and somatic cells throughout fetal and postnatal life. BMP signals are relayed by SMAD proteins, transcription factors that translocate to the nucleus upon ligand stimulation. We show that BMP signaling in the testis may be regulated by...

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PMID: 18069690
DOI: 10.1002/dvdy.21401

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