Article
Evaluation of the serotonergic genes htr1A, htr1B, htr2A, and slc6A4 in aggressive behavior of golden retriever dogs.
Behavior genetics - 1 Jan 2008
van den Berg L, Vos-Loohuis M, Schilder M B H, van Oost B A, Hazewinkel H A W, Wade C M, Karlsson E K, Lindblad-Toh K, Liinamo A E, Leegwater P A J
Abstract excerpt
Aggressive behavior displays a high heritability in our study group of Golden Retriever dogs. Alterations in brain serotonin metabolism have been described in aggressive dogs before. Here, we evaluate whether four genes of the canine serotonergic system, coding for the serotonin receptors 1A, 1B, and 2A, and the serotonin transporter, could play a major role in aggression in Golden Retrievers. We performed...
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