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Multilineage Potential of Stable Human Mesenchymal Stem Cell Line Derived from Fetal Marrow

5 Dec 2007

Abstract excerpt

Human bone marrow contains two major cell types, hematopoietic stem cells (HSCs) and mesenchymal stem cells (MSCs). MSCs possess self-renewal capacity and pluripotency defined by their ability to differentiate into osteoblasts, chondrocytes, adipocytes and muscle cells. MSCs are also known to differentiate into neurons and glial cells in vitro, and in vivo following transplantation into the brain of animal models...

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PMID: 18060066
DOI: 10.1371/journal.pone.0001272

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