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Article

Gravitational unloading induces an anti-angiogenic phenotype in human microvascular endothelial cells.

Journal of cellular biochemistry - 1 May 2008

Mariotti Massimo, Maier Jeanette A M

Abstract excerpt

Creating conditions similar to those occurring during exposure of cells to microgravity modulates endothelial functions. We have previously demonstrated that human macrovascular endothelial cells in simulated hypogravity proliferate faster than controls, partly because they downregulate interleukin 1alpha. On the contrary, murine microvascular endothelial cells are growth inhibited in simulated hypogravity, and...

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Identifiers

PMID: 17979129
DOI: 10.1002/jcb.21605

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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