Article
Prevalence of pyruvate kinase deficiency among the south Iranian population: quantitative assay and molecular analysis.
Blood cells, molecules & diseases - 1 Jan 2000
Yavarian M, Karimi M, Shahriary M, Afrasiabi A R
Abstract excerpt
We present the results of screening for pyruvate kinase (PK) deficiency on a cohort of 146 patients pre-selected from 4017 individuals by hematological index analysis. On average the PK activity levels measured in this cohort study were about 1.9% IU/g Hb while the activity measured in 85 healthy adults with normal erythrocyte indexes was in the range of 3.9-9.8 IU/g Hb. We were able to define 14 different...
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