Article
Detection of HCV by PCR in serum and PBMC of patients with hepatitis C after treatment.
The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases - 1 Oct 2007
Cavalheiro Norma de Paula, Filgueiras Thelma Cristina, Melo Carlos Eduardo, Morimitsu Suzana Rie, de Araújo Evaldo Stanislau Affonso, Tengan Fátima Mitiko, Barone Antonio Alci
Abstract excerpt
Although hepatitis C is mainly hepatotropic, some studies suggest that hepatitis C virus (HCV) infects peripheral blood mononuclear cells (PBMC), using them as a reservoir, which might contribute to the development of resistance to treatment. Fifty-four hepatitis-C patients, who had been submitted to treatment, were selected. Blood samples were collected on the same day for the detection of HCV RNA in serum and...
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