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Article

PLETHORA proteins as dose-dependent master regulators of Arabidopsis root development.

Nature - 25 Oct 2007

Galinha Carla, Hofhuis Hugo, Luijten Marijn, Willemsen Viola, Blilou Ikram, Heidstra Renze, Scheres Ben

Abstract excerpt

Factors with a graded distribution can program fields of cells in a dose-dependent manner, but no evidence has hitherto surfaced for such mechanisms in plants. In the Arabidopsis thaliana root, two PLETHORA (PLT) genes encoding AP2-domain transcription factors have been shown to maintain the activity of stem cells. Here we show that a clade of four PLT homologues is necessary for root formation. Promoter activity...

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Identifiers

PMID: 17960244
DOI: 10.1038/nature06206

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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