Article
Autism-related routines and rituals associated with a mitochondrial aspartate/glutamate carrier SLC25A12 polymorphism.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Apr 2008
Silverman Jeremy M, Buxbaum Joseph D, Ramoz Nicolas, Schmeidler James, Reichenberg Abraham, Hollander Eric, Angelo Gary, Smith Christopher J, Kryzak Lauren A
Abstract excerpt
Evidence for a genetic association between autism and two single nucleotide polymorphisms (SNPs), rs2056202 and rs2292813, in the mitochondrial aspartate/glutamate carrier (SLC25A12) gene led us to ask whether any of the four previously identified familial traits in autism spectrum disorders (ASD) varied by these SNPs. In 355 ASD cases from 170 sibships we examined levels of the four traits in these SNPs using...
Read the complete abstract on PubMed