Article
The Fusarium toxin deoxynivalenol disrupts phenotype and function of monocyte-derived dendritic cells in vivo and in vitro.
Immunobiology - 1 Jan 2007
Bimczok Diane, Döll Susanne, Rau Henriette, Goyarts Tanja, Wundrack Nicole, Naumann Michael, Dänicke Sven, Rothkötter Hermann-Josef
Abstract excerpt
The trichothecene mycotoxin deoxynivalenol (DON) causes systemic immuno-suppression in pigs and possibly also in humans after chronic dietary exposure. Since the outcome of every immune response is largely controlled by dendritic cells (DC), we hypothesised that a direct influence of DON on DC fu...
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