Article
Phenotypic differences between red pulp capillary and sinusoidal endothelia help localizing the open splenic circulation in humans.
Histochemistry and cell biology - 1 Nov 2007
Steiniger Birte, Stachniss Vitus, Schwarzbach Hans, Barth Peter J
Abstract excerpt
The distribution of capillaries, sinuses and larger vessels was investigated by immunohistology in paraffin sections of 12 adult human spleens using a panel of antibodies. Double staining for CD34 and CD141 (thrombomodulin) revealed that capillary endothelia in the cords of the splenic red pulp and at the surface of follicles were CD34(+)CD141(-), while red pulp sinus endothelia had the phenotype CD34(-)CD141(+)....
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