Article
Nectin and Nectin-Like Molecules: Biology and Pathology
1 Jan 2007
Abstract excerpt
Nectins and nectin-like molecules (Necls) are structurally related transmembrane proteins primarily involved in cell adhesion. Nectins and afadin, the adaptor or anchoring protein, stabilize the epithelium and endothelium and establish apical-basal polarity of epithelial cells, independently or in cooperation with other cell adhesion molecules. Necls facilitate cell-cell communication implicated in cell movement...
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