Article
Cystic fibrosis transmembrane conductance regulator (CFTR) gene 5T allele may protect against prostate cancer: a case-control study in Chinese Han population.
Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society - 1 May 2008
Qiao Di, Yi Long, Hua Lixin, Xu Zheng, Ding Yi, Shi Dongquan, Ni Ligang, Song Ninghong, Wang Yong, Wu Hongfei
Abstract excerpt
BACKGROUND: Cystic fibrosis transmembrane conductance regulator (CFTR) is expressed in a wide variety of epithelial cells including the prostate subglandular epithelia. Previous studies have suggested that CFTR mutations and polymorphisms may be associated with several cancers. Mutations and polymorphisms in the CFTR gene are responsible for cystic fibrosis (CF), and the incidence of prostate cancer in CF...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.