Article
High load for most high risk human papillomavirus genotypes is associated with prevalent cervical cancer precursors but only HPV16 load predicts the development of incident disease.
International journal of cancer - 15 Dec 2007
Gravitt Patti E, Kovacic Melinda Butsch, Herrero Rolando, Schiffman Mark, Bratti Concepcion, Hildesheim Allan, Morales Jorge, Alfaro Mario, Sherman Mark E, Wacholder Sholom, Rodriguez Ana-Cecilia, Burk Robert D
Abstract excerpt
Cervicovaginal human papillomavirus (HPV) viral load has been purported as a potential marker for the detection of high-grade cervical intraepithelial neoplasia or cancer (>/=CIN2). To examine disease association with type-specific viral load for the full-range of anogenital HPV infections, we conducted cross-sectional and prospective analyses of approximately 2,000 HPV-infected women from a 10,000-woman...
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