Article
Molecular Subgroup of Primary Prostate Cancer Presenting with Metastatic Biology.
European urology - 1 Oct 2017
Walker Steven M, Knight Laura A, McCavigan Andrena M, Logan Gemma E, Berge Viktor, Sherif Amir, Pandha Hardev, Warren Anne Y, Davidson Catherine, Uprichard Adam, Blayney Jaine K, Price Bethanie, Jellema Gera L, Steele Christopher J, Svindland Aud, McDade Simon S, Eden Christopher G, Foster Chris, Mills Ian G, Neal David E, Mason Malcolm D, Kay Elaine W, Waugh David J, Harkin D Paul, Watson R William, Clarke Noel W, Kennedy Richard D
Abstract excerpt
BACKGROUND: Approximately 4-25% of patients with early prostate cancer develop disease recurrence following radical prostatectomy. OBJECTIVE: To identify a molecular subgroup of prostate cancers with metastatic potential at presentation resulting in a high risk of recurrence following radical prostatectomy. DESIGN, SETTING, AND PARTICIPANTS: Unsupervised hierarchical clustering was performed using gene expression...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.