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Article

Inherited prion disease with 5-OPRI: phenotype modification by repeat length and codon 129.

Neurology - 21 Aug 2007

Mead S, Webb T E F, Campbell T A, Beck J, Linehan J M, Rutherfoord S, Joiner S, Wadsworth J D F, Heckmann J, Wroe S, Doey L, King A, Collinge J

Abstract excerpt

BACKGROUND: Human prion diseases have sporadic, acquired and inherited etiologies and show considerable phenotypic heterogeneity. An individual inherited prion disease offers an opportunity to study the determinants of this clinicopathologic heterogeneity among individuals with the same causal mu...

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Source

Identifiers

PMID: 17709704
DOI: 10.1212/01.wnl.0000267642.41594.9d

Genes

PRNP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-17709704-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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