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Article

Regulation of ubiquitin-proteasome system mediated degradation by cytosolic stress.

Molecular biology of the cell - 1 Nov 2007

Kelly Sean M, Vanslyke Judy K, Musil Linda S

Abstract excerpt

ER-associated, ubiquitin-proteasome system (UPS)-mediated degradation of the wild-type (WT) gap junction protein connexin32 (Cx32) is inhibited by mild forms of cytosolic stress at a step before its dislocation into the cytosol. We show that the same conditions (a 30-min, 42 degrees C heat shock...

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Identifiers

PMID: 17699585
DOI: 10.1091/mbc.e07-05-0487
PMCID: PMC2043544

Genes

CFTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17699585-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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