Article
Screening for MELAS mutations in young patients with stroke of undetermined origin.
Arquivos de neuro-psiquiatria - 1 Jun 2007
Conforto Adriana Bastos, Yamamoto Fabio Iuji, Oba-Shinjo Sueli Mieko, Pinto Julio Guy C, Hoshino Maurício, Scaff Milberto, Marie Suely Kazue Nagahashi
Abstract excerpt
PURPOSE: It has been suggested that mitochondrial disease may be responsible for a substantial proportion of strokes of indetermined origin. We have preliminarily screened for MELAS (mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes) mutations in young patients with cryptogenic strokes. METHOD: The mitochondrial mutations A3243G and T3271C were investigated in 38 subjects aged less than...
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