Evolving Epidemiology of <i>Pseudomonas Aeruginosa</i> and the <i>Burkholderia Cepacia</i> Complex in Cystic Fibrosis Lung Infection

Abstract excerpt

The morbidity and mortality of patients with cystic fibrosis (CF) is primarily determined by chronic and debilitating lung infections caused by a surprisingly narrow spectrum of bacterial pathogens. Pseudomonas aeruginosa is by far the most prevalent life-threatening CF pathogen. In the absence of aggressive early therapy, it infects the majority of adult patients and determines long-term survival. The...

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