Article
Helicobacter pylori infection and chronic immune thrombocytopenic purpura: long-term results of bacterium eradication and association with bacterium virulence profiles.
Blood - 1 Dec 2007
Emilia Giovanni, Luppi Mario, Zucchini Patrizia, Morselli Monica, Potenza Leonardo, Forghieri Fabio, Volzone Francesco, Jovic Gordana, Leonardi Giovanna, Donelli Amedea, Torelli Giuseppe
Abstract excerpt
Eradication of Helicobacter pylori may lead to improvement of chronic immune thrombocytopenic purpura (ITP), although its efficacy over time is uncertain. We report the results of H pylori screening and eradication in 75 consecutive adult patients with ITP. We also used molecular methods to investigate lymphocyte clonality and H pylori genotypes in the gastric biopsies from 10 H pylori-positive patients with ITP...
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