Article
Improvement of a CrtO-type of beta-carotene ketolase for canthaxanthin production in Methylomonas sp.
Metabolic engineering - 1 Jul 2007
Tang Xiao-Song, Shyr Joanne, Tao Luan, Sedkova Natalia, Cheng Qiong
Abstract excerpt
Two types of non-homologous beta-carotene ketolases (CrtW and CrtO) were previously described. We report improvement of a CrtO-type of beta-carotene ketolase for canthaxanthin production in a methylotrophic bacterium, Methylomonas sp. 16a, which could use the C1 substrate (methane or methanol) as sole carbon and energy source. The crtO gene from Rhodococcus erythropolis was improved for canthaxanthin production...
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