BRCA1, BRCA2, TP53, and CDKN2A germline mutations in patients with breast cancer and cutaneous melanoma.

doi:10.1007/s10689-007-9143-y

Article

BRCA1, BRCA2, TP53, and CDKN2A germline mutations in patients with breast cancer and cutaneous melanoma.

Familial cancer - 1 Jan 2007

Monnerat Christian, Chompret Agnès, Kannengiesser Caroline, Avril Marie-Françoise, Janin Nicolas, Spatz Alain, Guinebretière Jean-Marc, Marian Catalin, Barrois Michel, Boitier Françoise, Lenoir Gilbert M, Bressac-de Paillerets Brigitte

Abstract excerpt

PURPOSE: From epidemiological studies it appears that breast cancer (BC) and cutaneous melanoma (CMM) in the same individual occur at a higher frequency than expected by chance. Genetic factors common to both cancers can be suspected. Our goal was to estimate the involvement of "high risk" genes...

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