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Article

Laser-scanning velocimetry: a confocal microscopy method for quantitative measurement of cardiovascular performance in zebrafish embryos and larvae.

BMC biotechnology - 10 Jul 2007

Malone Michael H, Sciaky Noah, Stalheim Lisa, Hahn Klaus M, Linney Elwood, Johnson Gary L

Abstract excerpt

BACKGROUND: The zebrafish Danio rerio is an important model system for drug discovery and to study cardiovascular development. Using a laser-scanning confocal microscope, we have developed a non-invasive method of measuring cardiac performance in zebrafish embryos and larvae that obtains cardiovascular parameters similar to those obtained using Doppler echocardiography in mammals. A laser scan line placed...

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PMID: 17623073
DOI: 10.1186/1472-6750-7-40
PMCID: PMC1955438

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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