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Antibodies from Women Immunized with Gardasil ® Cross-Neutralize HPV 45 Pseudovirions

1 Jul 2007

Abstract excerpt

Human papillomavirus (HPV) types 6, 11, 16 and 18 L1 virus-like particles (VLPs) have been used to generate the prophylactic quadrivalent vaccine, Gardasil®. There is a high degree of homology within the L1 major capsid protein sequence of genital HPV types and it is therefore likely that there is a substantial degree of antigenic similarity of the surface exposed epitopes on the virion particles or on VLPs. It...

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PMID: 17611417
DOI: 10.4161/hv.3.4.4058

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