Article
Age-Related Changes in the Frequency of Mesenchymal Stem Cells in the Bone Marrow of Rats
1 Jun 2007
Abstract excerpt
Mesenchymal stem cells (MSCs) are pluripotent cells that can differentiate into endothelial, osteogenic, adipogenic, and other lineages. In spite of the broad interest, little is known about the variation of MSC number in relation to the age of the donor. The aim of this study was to investigate the age-associated variations of bone marrow (BM) MSCs using a rat model. Cell populations were characterized by flow...
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