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Article

Antisense RNA decreases AP33 gene expression and cytoadherence by T. vaginalis

3 Jul 2007

Abstract excerpt

BACKGROUND: Host parasitism by Trichomonas vaginalis is complex. Adherence to vaginal epithelial cells (VECs) is mediated by surface proteins. We showed before that antisense down-regulation of expression of adhesin AP65 decreased amounts of protein, which lowered levels of T. vaginalis adherence to VECs. We now perform antisense down-regulation of expression of the ap33 gene to evaluate and confirm a role for...

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PMID: 17608941
DOI: 10.1186/1471-2180-7-64

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