Article
Tissue plasminogen activator and plasminogen activator inhibitor-1 gene polymorphisms in patients with chronic periodontitis.
Journal of periodontology - 1 Jul 2007
Gürkan Ali, Emingil Gülnur, Saygan Buket Han, Cinarcik Serhat, Atilla Gül, Köse Timur, Berdeli Afig
Abstract excerpt
BACKGROUND: Tissue plasminogen activator (t-PA) and plasminogen activator inhibitor type 1 (PAI-1) are involved in the pathogenesis of periodontitis by controlling proteolytic events in the extracellular matrix. This study was designed to investigate the association of t-PA and PAI-1 gene polymorphisms with chronic periodontitis (CP). METHODS: One hundred eighty-nine subjects were included. Genomic DNA was...
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