Article
Complex patterns of the HIV-1 epidemic in Kuala Lumpur, Malaysia: evidence for expansion of circulating recombinant form CRF33_01B and detection of multiple other recombinants.
Virology - 25 Oct 2007
Wang Bin, Lau Katherine A, Ong Lai-Yee, Shah Meet, Steain Megan C, Foley Brian, Dwyer Dominic E, Chew Choo Beng, Kamarulzaman Adeeba, Ng Kee Peng, Saksena Nitin K
Abstract excerpt
The HIV protease-reverse transcriptase (PR-RT) (1047 bp), gp120-env (891 bp) and gp41-env (547 bp) regions from the plasma of 115 HIV-1-infected patients in Kuala Lumpur (KL), Malaysia were sequenced. Detailed phylogenetic and bootscanning analyses were performed to determine the mosaic structure of the HIV-1 strains and their recombination breakpoint(s). Among the 50 patient samples in which all three regions...
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