Article
High-throughput genotyping of a common deletion polymorphism disrupting the TRY6 gene and its association with breast cancer risk.
BMC genetics - 29 Jun 2007
Wagner Kerstin, Grzybowska Ewa, Butkiewicz Dorota, Pamula-Pilat Jolanta, Pekala Wioletta, Tecza Karolina, Hemminki Kari, Försti Asta
Abstract excerpt
BACKGROUND: Copy number polymorphisms caused by genomic rearrangements like deletions, make a significant contribution to the genomic differences between two individuals and may add to disease predisposition. Therefore, genotyping of such deletion polymorphisms in case-control studies could give important insights into risk associations. RESULTS: We mapped the breakpoints and developed a fluorescent fragment...
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