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Article

[Individual characteristics of human adaptation to intermittent hypoxia: possible role of genetic mechanisms].

Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) - 1 Jan 2007

Serebrovs'ka T V, Korkushko O V, Shatylo V B, Asanov E O, Ishchuk V O, Moiseienko Ie V, Drevyts'ka T I, Man'kovs'ka I M

Abstract excerpt

The majority of the adaptation processes to hypoxia is based on transcriptional regulation by hypoxia-inducible factors--HIFs. Recently the allele polymorphism of oxygen-dependent degradation domain of HIF-lalpha has been described. It consists in the replacement of cytosine for thymine in 1772 location (C1772-->T). The physiological significance of such replacement is obscure. In the investigation of 26 healthy...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 17595907

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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