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Are interrupted SCA2 CAG repeat expansions responsible for parkinsonism?

Neurology - 20 Nov 2007

Charles P, Camuzat A, Benammar N, Sellal F, Destée A, Bonnet A-M, Lesage S, Le Ber I, Stevanin G, Dürr A, Brice A

Abstract excerpt

BACKGROUND: Autosomal dominant parkinsonism (ADP) is caused in a large percentage of familial and sporadic cases by mutations in the LRRK2 gene, particularly G2019S. It is also caused by mutations in genes associated with autosomal dominant cerebellar ataxia (ADCA), notably CAG/CAA repeat expansions in SCA2. METHODS: We screened 164 families with ADP for expansions in the SCA2, 3, and 17 genes and for the G2019S...

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PMID: 17568014
DOI: 10.1212/01.wnl.0000269323.21969.db

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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