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Article

Centrin1 Is Required for Organelle Segregation and Cytokinesis in <i>Trypanosoma brucei</i>

14 Jun 2007

Abstract excerpt

Centrin is a calcium-binding centrosome/basal body-associated protein involved in duplication and segregation of these organelles in eukaryotes. We had shown that disruption of one of the centrin genes (centrin1) in Leishmania amastigotes resulted in failure of both basal body duplication and cytokinesis. Here, we undertook to define the role of centrin1 (TbCen1) in the duplication and segregation of basal body...

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PMID: 17567955
DOI: 10.1091/mbc.e07-01-0022

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