Article
Detection of Four <i>Plasmodium</i> Species by Genus- and Species-Specific Loop-Mediated Isothermal Amplification for Clinical Diagnosis
14 Jun 2007
Abstract excerpt
Loop-mediated isothermal amplification (LAMP), a novel nucleic acid amplification method, was developed for the clinical detection of four species of human malaria parasites: Plasmodium falciparum, P. vivax, P. malariae, and P. ovale. We evaluated the sensitivity and specificity of LAMP in comparison with the results of microscopic examination and nested PCR. LAMP showed a detection limit (analytical sensitivity)...