Large-scale copy number variants (CNVs): distribution in normal subjects and FISH/real-time qPCR analysis.

doi:10.1186/1471-2164-8-167

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Article

Large-scale copy number variants (CNVs): distribution in normal subjects and FISH/real-time qPCR analysis.

BMC genomics - 12 Jun 2007

Qiao Ying, Liu Xudong, Harvard Chansonette, Nolin Sarah L, Brown W Ted, Koochek Maryam, Holden Jeanette J A, Lewis M E Suzanne, Rajcan-Separovic Evica

Abstract excerpt

BACKGROUND: Genomic copy number variants (CNVs) involving >1 kb of DNA have recently been found to be widely distributed throughout the human genome. They represent a newly recognized form of DNA variation in normal populations, discovered through screening of the human genome using high-throughput and high resolution methods such as array comparative genomic hybridization (array-CGH). In order to understand...

Topics

Black People
Female
Gene Expression Profiling
Gene Expression Regulation
Genetic Variation
Hispanic or Latino
Humans
In Situ Hybridization, Fluorescence
Male
Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Nucleic Acid Hybridization

Polymerase Chain Reaction

Polymorphism, Genetic

Sequence Analysis, DNA

White People

Black or African American

Source

Open in PubMed Open full text

Identifiers

PMID: 17565693
DOI: 10.1186/1471-2164-8-167
PMCID: PMC1920519

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