Article
The two-pore channel TPK1 gene encodes the vacuolar K+ conductance and plays a role in K+ homeostasis.
Proceedings of the National Academy of Sciences of the United States of America - 19 Jun 2007
Gobert Anthony, Isayenkov Stanislav, Voelker Camilla, Czempinski Katrin, Maathuis Frans J M
Abstract excerpt
The Arabidopsis thaliana genome contains five genes that encode two pore K+ (TPK) channels. The most abundantly expressed isoform of this family, TPK1, is expressed at the tonoplast where it mediates K+ -selective currents between cytoplasmic and vacuolar compartments. TPK1 open probability depends on both cytoplasmic Ca2+ and cytoplasmic pH but not on the tonoplast membrane voltage. The channel shows intrinsic...
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