Article
Iron storage disease: facts, fiction and progress.
Blood cells, molecules & diseases - 1 Jan 2000
Beutler Ernest
Abstract excerpt
There are many forms of iron storage disease, some hereditary and some acquired. The most common of the hereditary forms is HFE-associated hemochromatosis, and it is this disorder that is the main focus of this presentation. The body iron content is regulated by controlling absorption, and studies in the past decade have clarified, in part, how this regulation functions. A 25-amino-acid peptide hepcidin is...
Topics
- Antimicrobial Cationic Peptides
- Cation Transport Proteins
- Genetic Predisposition to Disease
- Hemochromatosis
- Hepcidins
- Humans
- Penetrance
- Ferroportin