Differential enrichment of simple sequence repeats in selected Alzheimer-associated genes.

Abstract excerpt

The involvement of beta-amyloid (Abeta) in the pathogenesis of Alzheimer's disease (AD) has been well documented. In addition, a significant degree of information has been documented regarding the genetics of Abeta production and aggregation in familial forms of AD (FADs). However, the information regarding the causes or mechanism(s) responsible for Abeta accumulation in non-FADs is not as extensive and requires...

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