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Analysis of Intraviral Protein-Protein Interactions of the SARS Coronavirus ORFeome

23 May 2007

Abstract excerpt

The severe acute respiratory syndrome coronavirus (SARS-CoV) genome is predicted to encode 14 functional open reading frames, leading to the expression of up to 30 structural and non-structural protein products. The functions of a large number of viral ORFs are poorly understood or unknown. In order to gain more insight into functions and modes of action and interaction of the different proteins, we cloned the...

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PMID: 17520018
DOI: 10.1371/journal.pone.0000459

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