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Functional characterization of AtATM1, AtATM2, and AtATM3, a subfamily of Arabidopsis half-molecule ATP-binding cassette transporters implicated in iron homeostasis.

The Journal of biological chemistry - 20 Jul 2007

Chen Sixue, Sánchez-Fernández Rocío, Lyver Elise R, Dancis Andrew, Rea Philip A

Abstract excerpt

The functional capabilities of one of the smallest subfamilies of ATP-binding cassette transporters from Arabidopsis thaliana, the AtATMs, are described. Designated AtATM1, AtAATM2, and AtATM3, these half-molecule ABC proteins are homologous to the yeast mitochondrial membrane protein ATM1 (ScATM1), which is clearly implicated in the export of mitochondrially synthesized iron/sulfur clusters. Yeast ATM1-deficient...

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PMID: 17517886
DOI: 10.1074/jbc.M702383200

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