Association between nasal carriage of Staphylococcus aureus and the human complement cascade activator serine protease C1 inhibitor (C1INH) valine vs. methionine polymorphism at amino acid position 480.

doi:10.1111/j.1574-695X.2007.00250.x

Article

Association between nasal carriage of Staphylococcus aureus and the human complement cascade activator serine protease C1 inhibitor (C1INH) valine vs. methionine polymorphism at amino acid position 480.

FEMS immunology and medical microbiology - 1 Aug 2007

Emonts Marieke, de Jongh Christa E, Houwing-Duistermaat Jeanine J, van Leeuwen Willem B, de Groot Ronald, Verbrugh Henri A, Hermans Peter W M, van Belkum Alex

Abstract excerpt

Staphylococcus aureus produces compounds that interfere with complement deposition. We hypothesized that humans have developed countermeasures to staphylococcal complement evasion and we screened for single nucleotide polymorphisms in the serine protease C1 inhibitor (C1INH) gene at amino acid position 480 (valine vs. methionine) and nasal carriage of S. aureus. In our study cohort, 38 individuals were...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Complement C1 Inhibitor Protein

Share to Methionine

Share to Nose

Share to Serpins

Share to Staphylococcal Infections

Share to Valine

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 8 closest

Association between nasal carriage of Staphylococcus aureus and the human complement cascade activator serine protease C1 inhibitor (C1INH) valine vs. methionine polymorphism at amino acid position 480.PMID 17498209Read

Are host genetics the predominant determinant of persistent nasal Staphylococcus aureus carriage in humans?Semantic proximity Read

Complement component C7 deficiency in a Spanish family.Semantic proximity Read

Staphylococcal Proteases Aid in Evasion of the Human Complement SystemSemantic proximity Read

High prevalence of complement component C6 deficiency among African-Americans in the South-eastern USASemantic proximity Read

Human Factor in<i>Staphylococcus aureus</i>Nasal CarriageSemantic proximity Read

Staphylococcus aureus nasal carriage is associated with glucocorticoid receptor gene polymorphisms.Semantic proximity Read

Carriage of<i>Staphylococcus aureus</i>among 104 healthy persons during a 19-month periodSemantic proximity Read

Factors associated with Staphylococcus aureus nasal carriage among healthy people in Northern China.Semantic proximity Read