Article
Are host genetics the predominant determinant of persistent nasal Staphylococcus aureus carriage in humans?
The Journal of infectious diseases - 15 Sept 2010
Ruimy Raymond, Angebault Cécile, Djossou Félix, Dupont Claire, Epelboin Loïc, Jarraud Sophie, Lefevre Laurence Armand, Bes Michèle, Lixandru Brandusa Elena, Bertine Mélanie, El Miniai Assiya, Renard Magaly, Bettinger Régis Marc, Lescat Mathilde, Clermont Olivier, Peroz Gilles, Lina Gerard, Tavakol Mehri, Vandenesch François, van Belkum Alex, Rousset François, Andremont Antoine
Abstract excerpt
BACKGROUND: Staphylococcus aureus nasal carriage is influenced by multifactorial interactions which are difficult to study in open populations. Therefore, we concomitantly assessed the epidemiological, microbiological, and human-genetic carriage-related factors in a nearly closed population. METHODS: In 2006 and 2008, we collected nasal S. aureus strains, human DNA, and epidemiological data from 154 adult Wayampi...
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